Zolidd
Enhancing the bone holding power of orthopedic implants
AddBIO is developing Zolidd, a unique biomaterial product that improves the fixation of orthopedic implants and screws through strengthening of the surrounding bone.
Implant loosening causes patient suffering and is a resource demanding problem, leading to high costs for patient care and re-operations. Compromised bone quality is a significant part of the problem, and improving the strength of the bone surrounding the implant therefore lowers the risk for loosening and other complications.
Zolidd is the first application of the FibMat technology, a propriatry platform for local drug availability from orthopedic implants. The bone strengthening effect is achieved by binding a bisphosphonate drug onto the implant. Bisphosphonates are already approved drugs that since long have been given systemically to osteoporotic patients to improve bone quality. Zolidd now enables these drugs to be released locally, directly from the implant.
Zolidd is compatible with most types of orthopedic implants as it strengthens the bone without changeing the underlying properties of the implant itself. Zolidd is aimed at trauma, spine, and reconstructive orthopedics as well as dental implants. Efficacy has been shown in a dental clinical study. Two additional clinical studies are currently on-going, an extended dental study as well as an osteotomy study.
